Benvenuti in queste pagine dedicate a scienza ed arte. Amelia Carolina Sparavigna

Saturday, January 8, 2011

Coronary stent

Most balloon angioplasty procedures include the insertion of tiny cylindrical wire mesh structures, called cardiovascular stents*, into the artery to prevent the elastic recoil that follows arterial dilatation. The scaffolding characteristics of the stent provide strength to the artery wall. However, vascular injury during stent deployment and/or recognition of the stent as a foreign material triggers neointimal hyperplasia, causing re-closure of the artery. A recent advancement to counteract restenosis is to employ drug-eluting stents to locally deliver immunosuppressant andantiproliferative drugs.  Furthermore,  auxetic (negative Poisson's ratio) stent structures were proposed that exhibits high circumferential strength in its expanded configuration and low flexural rigidity in its crimped configuration. 

*A stent is an artificial tubular structure inserted into a natural passage/conduit to prevent, or counteract, a localized flow constriction. The term may also refer to a tube used to temporarily hold such a natural conduit open to allow access for surgery.
See also http://en.wikipedia.org/wiki/Coronary_stent

Note the structure of the two stents. Stretching the tube corresponds in increasing the diameter. This image has been obtained after elaboration of the original one: Zwei Stents von schräg vorne mit Zentimetermaß. Ort der Aufnahme: Baden-Baden, Deutschland, Frank C. Müller.