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Benvenuti in queste pagine dedicate a scienza, storia ed arte. Amelia Carolina Sparavigna, Torino

Thursday, June 25, 2020

Un farmaco da Nobel

Abbiamo un farmaco che può salvare delle vite ma in Italia lo usiamo per la cura della pelle
La denuncia del direttore del Centro di Malattie Tropicali dell'Ospedale di Negrar, nel Veronese: "L'Ivermectina è riconosciuta dall'Ema ed è utilizzata da tempo in Usa ed in molti Paesi europei per scongiurare l'allarme scabbia portata dai profughi. Ma inspiegabilmente da noi è solo una crema contro i rossori"
"Una dose di compresse di Ivermectina per scongiurare l'allarme scabbia portata dai profughi. Ma anche per curare decine di migliaia di italiani colpiti dalla “Strongiloidosi” che può diventare mortale. O per combattere gravi virus come zika, febbre gialla, duengue e anche malaria (in questo caso è tossico per le zanzare). Solo che quel farmaco, in Italia, non c'è, perché non è ancora stato riconosciuto dall'Aifa, l'Agenzia italiana del farmaco. E questo, incredibilmente, dopo che per aver scoperto la sua base, l'Avermectina, nel 2015 i ricercatori William Campbell e Satoshi Ōmura vennero premiati con il Nobel per la Medicina."

Ecco il link alla nota stampa della Fondazione Nobel
archiviata  http://archive.is/JMRhi

"William C. Campbell and Satoshi Ōmura discovered a new drug, Avermectin, the derivatives of which have radically lowered the incidence of River Blindness and Lymphatic Filariasis, as well as showing efficacy against an expanding number of other parasitic diseases. Tu Youyou discovered Artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from Malaria. These two discoveries have provided humankind with powerful new means to combat these debilitating diseases that affect hundreds of millions of people annually. The consequences in terms of improved human health and reduced suffering are immeasurable."

Si legga l'articolo

Proc Jpn Acad Ser B Phys Biol Sci. 2011 Feb 10; 87(2): 13–28.
doi: 10.2183/pjab.87.13
PMCID: PMC3043740
PMID: 21321478
Ivermectin, ‘Wonder drug’ from Japan: the human use perspective
Andy CRUMP and Satoshi ŌMURA

Tuesday, June 2, 2020

Pagine di pergamena: Sapevate che i cavalieri romani usavano maschere d...

Pagine di pergamena: Sapevate che i cavalieri romani usavano maschere d...: Il ritrovamento alcuni anni fa di una maschera facciale laminata d’argento sul luogo delle celebre battaglia della foresta di Teutoburgo ...



https://commons.wikimedia.org/wiki/File:Kalkriese_face_mask_for_Roman_cavalry_helmet,_Museum_und_Park_Kalkriese,_Germany_(9603028191).jpg

This military face mask is one of the most exceptional finds at the Kalkriese battle grounds. As 'The Kalkriese Type' it stands as the prime example for masks with a small face, the eyes are not particularly even, but give good sight. It is made of iron with silver overlay. The silver have been stripped off. At the chin you can find a fixing for the helmet, which probably possessed cheekprotectors. The 'Kalkriese Type' and the 'Noviomagus Kopsplateau Type' are the oldest facial helmets knows in the Roman army. First part, 1st century AD. Date 15 August 2013, 15:21 Source Kalkriese face mask for Roman cavalry helmet, Museum und Park Kalkriese, Germany Uploaded by Marcus Cyron Author Carole Raddato from FRANKFURT, Germany


Friday, May 29, 2020

Flower of Life




Flower of Life, Six-Fold Symmetry and Honeycomb Packing of Circles in the Mycenaean Geometry

Amelia Carolina Sparavigna & Mauro Maria Baldi

March 29, 2016

Abstract
In this paper we discuss the geometric decoration of some Mycenaean artifacts, having a remarkable six-fold symmetry, probably suggested by the observation of the natural form of the honeycomb of beehives. In particular, we will discuss a decoration of a gold roundel, made by means of a compass, that looks like the Flower of Life of sacred geometry.



Dodecahedron


Il solido platonico che preferisco

Monday, May 18, 2020

Favism, that is G6PD deficiency, and drugs for Covid-19

Favism, that is G6PD deficiency, and drugs for Covid-19

A document, vital for people having Glucose-6-phosphate dehydrogenase deficiency (favism) is available. The link is https://www.epicentro.iss.it/coronavirus/pdf/en-report-covid-19-14-2020.pdf . In this document it is told that "Chloroquine and hydroxychloroquine currently applied to COVID-19 patients should be avoided in those with severe G6PD deficiency as they could trigger a hemolytic crisis in the patient". Other very important references are also given. Besides Chloroquine and Hydroxychloroquine, Primaquine and 8-Aminoquinolines are considered.

https://web.archive.org/web/20200518070228/https://www.epicentro.iss.it/coronavirus/pdf/en-report-covid-19-14-2020.pdf

Saturday, May 16, 2020

On the observation of Hypokalemia in Covid-19

On the observation of Hypokalemia in Covid-19: Hypokalemia is a low level of potassium in the blood serum. Here a survey of literature about the observation of Hypokalemia in Covid-19. In particular we consider the study published in a MedRvix preprint 'Hypokalemia and clinical implications in patients with coronavirus disease 2019 (COVID-19)'.

Tuesday, May 12, 2020

Vitamin D for Covid-19?

Vitamin D for Covid-19?


A small survey of literature about Vitamin D and inhibition and expression of interleukins and tumor necrosis factors. Could Vitamin D have a possible role in Covid-19 Cytokine Release Syndrome? A study of its role when tocilizumab is used exists, and therefore Vitamin D could be considered when tocilizumab is involved in the mitigation of the cytokine storm. However, another question also exists and it is the following. Might Vitamin D induce antimicrobial peptides to reduce SARS-CoV-2 replication?

Covid-19 Cytokine Release Syndrome and Drugs

Covid-19 Cytokine Release Syndrome and Drugs

A survey of literature about the Cytokine Release Syndrome in Covid-19 and of some drugs used or proposed against it.

Saturday, May 9, 2020

Drugs used in Italy against Covid-19

Drugs used in Italy against Covid-19: Here a review concerning drugs used in Italy against Covid-19 and its effects on humans. The main source of information about trials is the Italian Government. Related links are given. From thse links, the names of trials and  drugs involved have been obtained. Some information and references about drugs have been collected from other web sites. References to scholar papers and news are also given. Drugs mentioned are Tocilizumab, Sarilumab, Siltuximab, Canakinumab, Baricitinib, Methylprednisolone, Selinexor, Hydroxychloroquine, Enoxaparin sodium, Solnatide,  Colchicine,  Emapalumab, Anakinra, Remdesivir, Camostat, Nafamostat, Ivermectin.